Small granules on the sides of the nose and chin need to be removed in a way according to their causes, such as corn rashes, acne, flat warts, etc. After diagnosis, choose medication, laser treatment, surgical treatment, and so on. 1. Corns: also known as fat grains, can lead to small particles on both sides of the nose and chin, the cause is not yet clear, may be related to heredity, inflammation and so on. Treatment can be done by having a professional doctor sterilize the area and pick out the contents with a cosmetic needle, or you can choose laser surgery to remove them. 2. Acne: It can be manifested as pimples, papules, etc. Small particles can appear on both sides of the nose and chin. For treatment, you can choose retinoic acid cream, adapalene gel for topical application, oral retinoic acid medication for those who need quick results, and acne can also be removed by acne clearing surgery. 3. flat warts: localized infection with human papilloma virus can cause flat warts, which appear on both sides of the nose and chin long small particles. The treatment can be topical imiquimod, but also cryotherapy, electrocautery, laser therapy or photodynamic therapy can be used to remove the warts. There are many reasons for the growth of small particles on both sides of the nose and chin, and it is recommended that the patient go to the hospital as soon as possible, and after a clear diagnosis, give standardized treatment, do not treat it indiscriminately, so as not to lead to adverse consequences.