Pancreatic relaxation is mainly considered to be the relaxation of pancreatic sphincter, and a large amount of gastric acid refluxes into the esophagus through the stomach, damaging the mucous membrane of the stomach and esophagus lining, manifesting as acid reflux, heartburn, retrosternal pain and other discomforts. When the patient’s cardia sphincter is relaxed, a large amount of gastric acid is produced after eating and drinking, which flows back into the esophagus together with food, resulting in nausea, vomiting and other discomforts. Gastric acid directly stimulates the esophageal wall and causes esophagitis, leading to severe acid reflux, heartburn, retrosternal pain and other discomforts. These symptoms tend to occur within half an hour after a meal, and if the symptoms are severe, there is also significant radiating pain in the form of chest and back pain. In addition, patients may also experience discomfort such as eructation (hiccups) and abdominal pain, which should be addressed when the patient notices the relaxation of the pancreatic sphincter to avoid delays in treatment.