Leprosy phobia is a clinical diagnosis of disease phobia. Leprosy phobia is a neurosis characterized by an intense fear of leprosy disease, and some patients are timid, shy, dependent, and introverted. How can such symptoms be detected? Disease horror check mainly for patients corresponding to the horror of the disease to do the relevant examination, such as fear of AIDS, need to do AIDS-related antigen antibody test; syphilis horror, need to do syphilis serologic test, genetic diagnostic techniques to detect syphilis spirochetes, syphilis antibody titer related experiments, etc.; leprosy horror, you need to carry out leprosy bacillus test, leprosy bacillus test and so on. Through these tests to determine the absence of disease, so as to dispel or reduce the patient’s concerns. Others: X-ray film, electrocardiogram, blood and urine tests, and so on. The pathogenesis is not well understood. The disease is generally recognized as an auto-compulsive neurosis. In the lack of knowledge of the disease, inappropriate propaganda, their own behavioral memory, as well as mental stimulation, trauma caused by psychological behavioral abnormalities, to the fear of disease as the content of the neuropsychiatric symptoms. The main measure of prevention is to maintain a good state of mind, improve psychological quality, master and understand the basic knowledge of the relevant diseases, avoid thinking nonsense, if you do consider signs of illness, please go to the hospital in time for examination, pay attention to early detection, early diagnosis and early treatment, to avoid long-term suspicion of suffering from a certain disease, which leads to psychological problems, causing mental trauma. If necessary, please seek timely help from a psychiatrist.