For babies born with high white blood cells and low muscle tone, it is recommended to seek medical advice as early as possible to understand the causes and, if necessary, carry out rehabilitation or give anti-infection treatment. 1. High white blood cells: If the white blood cells of a newborn baby are high, and if there are no other signs of discomfort, such as fever, cough and dyspnea, and if the baby’s feeding and mental state are relatively good, close observation is recommended, and no special treatment is usually needed. If the state of mind, breastfeeding is relatively poor, it is recommended to carry out blood culture tests, if necessary, give anti-infective drug treatment. 2. Low muscle tone: Newborn babies with low muscle tone need to know whether it is related to congenital diseases, ischemic-hypoxic encephalopathy, hypothyroidism and other factors. If ischemic-hypoxic encephalopathy leads to low muscle tone, it is recommended to carry out rehabilitation training, and part of the low muscle tone can be gradually recovered. To sum up, if a newborn baby has high white blood cells and low muscle tone, it is recommended to go to the pediatric internal medicine department of the hospital in time to find out the cause and give treatment if necessary.