Patients with emphysema feel weak mainly because of the lack of oxygen in the body. 1. The terminal bronchioles of emphysema patients are often destroyed, and alveolar rupture leads to enlargement and over-expansion of the alveolar cavity, destruction of the elastic fiber network of the alveolar wall leads to decreased elasticity, resulting in an increase in the amount of residual air in the alveoli and a decrease in the number of capillaries in the alveolar wall, which prevents effective air exchange, thus generating hypoxemia. 2. When emphysema is severe, it may lead to chronic obstructive pulmonary disease (COPD), obstructive ventilation dysfunction, and decreased activity endurance. 3. When there is an infection in the lungs, gas exchange in the lungs becomes more difficult and symptoms of malaise worsen. Patients with emphysema should go to the hospital in a timely manner and receive regular treatment under the guidance of a doctor to avoid further development of the disease.