Hyaline vascular type is one of the reactive lymphadenopathies of undetermined cause, which is relatively rare in clinical practice, and is characterized by significant enlargement of deep or superficial lymph nodes, and some cases may be accompanied by systemic symptoms and/or multi-systemic damages, and most of them have good results after surgical resection of the enlarged lymph nodes. Hyaline vascular type is divided into 3 types: Hyaline vascular type (HV), plasma cell type (PC) and mixed type. HV type is characterized by the increase of lymphoid follicles, there is extensive hyaline degeneration of capillary hyperplasia, and some of the lymphocytes can be arranged in layers around the center, such as “onion skin”, with the disappearance of the growth center and the disappearance of the lymphatic sinus or fibrosis. The PC type is characterized by a large number of mature plasma cells between lymphoid follicles, and hyaline degeneration of blood vessels is rare. The mixed type has the characteristics of the above two types and is commonly found in areas other than the lymph nodes. It is generally believed that the hyaline vascular type is more common, accounting for more than 90% of cases, and most of them do not have systemic symptoms and belong to the clinical focal type, and all three cases in our hospital belong to this type; while the plasma cell type is rare, less than 10%, and some of them are accompanied by systemic manifestations, and most of the multicentric type in the clinical type corresponds to this type.The onset of CD is diversified, and most of them are diagnosed with the symptoms of compression of the mass. The etiology of CD is unknown. The plasma cell type is thought to be related to infection and inflammation, and some authors have suggested that abnormalities in immunoregulation are the initiating factor for CD. 25% of cases of the central type are clinically confirmed to be associated with HHV-8 infection, and it is also thought that at least some of the CDs are at risk of B-cell malignant proliferation, and a few of the multicentric types may be transformed into malignant lymphomas, although in most of the cases the follow-up results do not show any malignant transformation.