Hyaline vascular type is one of the reactive lymphadenopathies of undetermined cause, which is relatively rare in clinical practice, and is characterized by significant enlargement of deep or superficial lymph nodes, and some cases may be accompanied by systemic symptoms and/or multi-systemic damages, and most of them have good results after surgical resection of the enlarged lymph nodes. Hyaline vascular type is divided into 3 types: Hyaline vascular type (HV), plasma cell type (PC) and mixed type. HV type is characterized by the increase of lymphoid follicles, there is extensive hyaline degeneration of capillary hyperplasia, and some of the lymphocytes can be arranged in layers around the center, such as “onion skin”, with the disappearance of the growth center and the disappearance of the lymphatic sinus or fibrosis. The PC type is characterized by a large number of mature plasma cells between lymphoid follicles, and hyaline degeneration of blood vessels is rare. The mixed type has the characteristics of the above two types and is commonly found in areas other than the lymph nodes. It is generally believed that the hyaline vascular type is more common, accounting for more than 90% of cases, and most of them do not have systemic symptoms and belong to the clinical focal type, and all three cases in our hospital belong to this type; while the plasma cell type is rare, less than 10%, and some of them are accompanied by systemic manifestations, and most of the multicentric type in the clinical type corresponds to this type.The onset of CD is diversified, and most of them are diagnosed with the symptoms of compression of the mass. The following diseases may cause hyaline vascular type: 1. Lymphoma Lymphoma is a malignant tumor originated from lymph nodes or lymphatic tissues. Clinical painless, progressive lymph node enlargement is the main manifestation. This disease can occur at any age, but the peak age of onset is 31~40 years old, in which the peak of non-Hodgkin’s lymphoma is slightly shifted forward. The ratio of male to female is 2~3:1. 2, chronic lymphadenitis Chronic lymphadenitis is mostly secondary to inflammatory lesions in the head, face and neck. Lymph nodes are enlarged to different degrees, scattered in the lateral neck area or submandibular and sub-chin areas. They may be slightly hard but with a smooth surface, able to move, and may have mild pressure or discomfort. Chronic lymphadenitis does not require treatment in person, and the examination should be performed with care to look for primary foci of inflammation. In addition to the regions of the neck the scalp, outer ear and hidden areas such as the mouth, tonsils and gums should also be carefully examined. Primary foci can also be found by pressing the lymphatic admittance zones of the enlarged lymph nodes.