AIDS is called acquired immunodeficiency syndrome, and the syndrome and its complications may manifest in a variety of ways, so there are very many complications of AIDS. AIDS can cause central nervous system infections, such as causing cryptococcal meningitis and tuberculous meningitis. The oral cavity can produce thrush, Candida infections, and can cause lung infections, such as Pneumocystis pneumonia, various fungal infections, and tuberculosis. It can cause intestinal infections, leading to a variety of diarrhea, and can have skin manifestations such as common Kaposi’s sarcoma, herpes zoster, seborrheic dermatitis, and herpes simplex. In addition to this, it can cause prolonged wasting, diarrhea, and prolonged fever, which is also a common manifestation of AIDS. In conclusion, AIDS can involve all organ systems, mainly because of its systemic immunity damage after each easy to infect the pathogenic bacteria. Therefore, there are many complications of AIDS, which can only be determined after a specialist diagnosis in a hospital.