Enlarged submandibular lymph nodes of kidney cancer may be caused by metastasis of kidney cancer, lymphadenitis, lymph node tuberculosis and lymphoma. 1. Kidney cancer metastasis: when kidney cancer has lymph node metastasis, it will not only show hematuria, lumbago, abdominal mass and other manifestations, but also have the symptom of swollen lymph nodes in neck or submandibular lymph nodes. 2. Lymphangitis: when hemolytic streptococcus or staphylococcus aureus infection occurs in submandibular lymph nodes of kidney cancer patients, there will be symptoms such as swollen lymph nodes and lymph node pain. 3. Lymph node tuberculosis: if kidney cancer patients infected with Mycobacterium tuberculosis will have lymph node tuberculosis, they may have symptoms such as swollen lymph nodes in neck or submandibular lymph nodes, night sweating and fever. 4. Lymphoma: If kidney cancer patients are complicated with lymph node cancer, they will not only have enlarged submandibular lymph nodes, but also have enlarged lymph nodes in other parts of the body, fever, weight loss, night sweating and other manifestations. It is suggested that kidney cancer patients with swollen submandibular lymph nodes need to consult doctor in time for examination, and the doctor will choose appropriate measures for treatment after clarifying the cause of the disease.