Minimally invasive interventional therapy has made rapid progress based on exhaustive research on the anatomy, biochemistry, biomechanics and imaging of the intervertebral disc. Compared with traditional surgical methods, minimally invasive interventional techniques have the advantages of less trauma, faster recovery, no damage to the normal structure of the spinal canal and no impact on the biological stability of the spine. For example, collagenase chemodissolution, radiofrequency ablation, ozone nucleus pulposus fusion, and minimally invasive intervertebral foraminoscopic treatment. 1.Collagenase chemical dissolution is under the monitoring and guidance of CT modern imaging equipment, collagenase, a new class of drugs, is accurately injected into the herniated disc site, and collagenase is utilized to dissolve the collagen molecules within the herniated material, dissolve the herniated material, and relieve the compression of nerves, so as to achieve the purpose of root treatment. 2.Radiofrequency ablation Under the accurate positioning of CT machine, the radiofrequency puncture needle with a diameter of about 0.7 mm is punctured into the nucleus pulposus of the main disc, and through the radiofrequency high-frequency electric current, the tip of the working tip is heated, and thermal coagulation destroys the tissues in the target area. Radiofrequency thermo-coagulation target treatment is a direct part of the protruding disease-causing nucleus pulposus denaturation, coagulation, contraction, volume reduction, lifting the nerve compression, while the warm effect of the damaged fibers, nerve root edema, inflammatory reaction in the spinal canal play a good therapeutic role, the symptoms of the treatment immediately after the reduction and disappearance.