Itching on both sides of the thighs may be caused by ringworm, eczema, solar urticaria and other diseases. 1. Ringworm: this disease is caused by dermatophytes, mostly seen in red trichophyton, which can be spread through direct contact or indirect contact. It usually occurs in the groin, buttocks and other places, and can be manifested as itching, edema, flaking and erythema on both sides of the thighs. 2. Eczema: the etiology of this disease is not clear, may be related to genetics, immune abnormalities, abnormal hormone levels, endocrine diseases, chronic infectious foci, etc. Patients may be allergic to beef, animal dander, pollen and other substances. Common symptoms are lesions manifested as erythema, edema, papules, itching, etc. The rash can be distributed in any part of the body, so some patients have itching on both sides of the thighs. 3. Solar urticaria: the occurrence of this disease is mainly associated with sunlight exposure, activation of the body’s immune cells, making vascular permeability enhancement, increased histamine secretion, the typical symptom is that the exposed skin will appear burning sensation, itching, erythema and other symptoms. If the patient wears shorts in the summer, it is easy to appear thighs itching performance. There are many reasons for the itching on both sides of the thighs, so it is necessary to go to the hospital to improve the examination and clarify the cause of the disease.