Female pubic tumescence refers to uterine prolapse, and the main clinical treatments are surgical treatments, such as Mann’s surgery, total uterine excision and vaginal repair, etc. Pharmacological treatments are limited, mainly for postmenopausal patients with atrophy of the vaginal mucosa, and the use of topical estrogenic preparations after surgery. Estrogen preparations generally include estradiol tablets, ethinyl estradiol cyproterone tablets, and nil estradiol tablets. If patients have mild symptoms, they can be treated with pelvic floor muscle exercises. Some patients can be treated with uterine supports, which support the uterus and vaginal walls to remain in the vagina without prolapsing. All of the above medications should be used under a doctor’s supervision and avoid self-medication. If the symptoms of uterine prolapse are severe, or if the symptoms continue without improvement, the patient should seek medical treatment in a timely manner.