Advantages of biologic treatments for psoriasis include rapid control of the disease, good efficacy, and few side effects, but these advantages are not seen in every patient. Some patients may also have disease progression and adverse reactions after using biologics. Psoriasis is a chronic scaly disease, the cause of which is mostly related to genetics, immunity and other factors, patients can follow the doctor’s instructions to inject biological agents to treat. Biological agents are a kind of targeted immunomodulators, and common drugs include etanercept, adalimumab, infliximab, stavudine, etc. They have the advantages of controlling the disease, good efficacy, quick effect, small side effects, and promoting the disappearance of rash. For psoriasis patients, biologics can help treat the disease, but it is recommended that patients go to a regular hospital to consult a doctor, use the medication under the doctor’s guidance, and avoid abusing the medication in case of abnormalities.