Long-term use of aspirin need to pay attention to the time of taking, adverse reactions, whether there is bleeding tendency, allergic reactions and other aspects. 1. Taking time: most people take aspirin enteric-coated tablets, enteric-coated tablets are recommended to be taken before meals is better, taken on an empty stomach will quickly enter the gastrointestinal tract, fast absorption, reduce gastrointestinal reactions. 2. Adverse reactions: there may be gastrointestinal reactions, such as nausea and vomiting or even lead to the occurrence of ulcers. So people with peptic ulcer are not recommended to take aspirin enteric-coated tablets. 3. With or without bleeding tendency: aspirin is a kind of anti-platelet aggregation drug, long-term use may lead to bleeding tendency. Therefore, in the process of taking, must observe whether there is bleeding gums, black stools, hematuria, etc., regular monitoring of coagulation function, once serious bleeding is recommended to stop taking drugs. 4. Allergic reaction: a few people will have an allergic reaction, immediately medication, if anaphylactic shock is immediately resuscitated. Aspirin needs to be taken under the guidance of a physician, do not take medication without authorization, so as not to delay the condition.