Urine microalbumin is high but kidney ultrasound is fine, according to the existence of chronic kidney disease, drug kidney injury, lupus nephritis and other conditions, as well as whether it is physiological proteinuria, to give the appropriate medication, life regulation, regular review and so on. 1. Chronic kidney disease: If the kidney disease is caused by chronic diseases, such as hypertension and diabetes, we need to control the blood pressure and blood sugar within the range, and take oral urinary protein-lowering drugs, such as irbesartan tablets, chlorosartan tablets, valsartan, etc. If the urinary microalbumin is caused by nephrotic syndrome, we need to apply hormone treatment, such as methylprednisolone tablets. 2. Pharmacological kidney injury: some patients take long-term oral kidney damage drugs, such as taking drugs containing Poria cocos, Guanmutong and other ingredients, or due to cancer application of chemotherapeutic drugs, etc., may appear urine microalbumin. You should have timely feedback with your doctor to adjust the medication or correct the urinary microalbumin, pay attention to high-quality protein diet, avoid exertion and excessive exercise, use diuretics cautiously, and avoid getting cold and staying up late. 3. Lupus nephritis: If you have systemic lupus erythematosus, urinary microalbumin need to do renal puncture pathology to make clear whether it is caused by lupus, and regularly review the blood sedimentation, blood routine, C-reactive protein and other laboratory indicators reflecting the activity of lupus, and the application of hydroxychloroquine and other medications to regulate immunity. In addition, such as strenuous exercise, eating a lot of meat caused by physiological proteinuria, can also appear high urinary microalbumin but renal ultrasound is fine, generally no special treatment, remove the trigger can be restored. All of the above drugs should be used in accordance with the doctor’s instructions. It is recommended that the patient go to the hospital in time to clarify the cause of the disease, and follow the doctor’s advice to timely symptomatic treatment.