Pain in the bone below the knee after playing ball, there are many reasons that can lead to this symptom, including meniscus injury, patellar ligament stop inflammation, tibial tuberosity chondritis and osteoarthritis, etc. The treatment generally includes rest and braking, physical therapy, medication surgical treatment, and so on. 1. Meniscus injury: first of all, the activities of the knee joint should be restricted, and at the same time, it can be combined with ultrashort wave therapy and microwave therapy. If the pain is obvious, oral non-steroidal anti-inflammatory drugs, such as Celecoxib and Loxoprofen Sodium, etc. can be taken. If the condition is serious, arthroscopic surgery should be considered. 2. Patellar ligament stop point inflammation: it is recommended to wear knee pads, and avoid squatting and going up and down stairs, if the pain is obvious, oral celecoxib, rosoprofen sodium and other non-steroidal anti-inflammatory drugs can be used, but also the use of extracorporeal shock wave treatment. 3. Tibial tuberosity osteochondritis dissecans: For tibial tuberosity osteochondritis dissecans, it is recommended to rest and brake in time, and at the same time, it can be combined with localized hot compresses to help reduce swelling and pain, which can be relieved on its own. Anti-inflammatory and pain relieving creams such as diclofenac diethylamide emulsion can also be used. Physiotherapy, massage and acupuncture can also be used according to the situation. 4. Osteoarthritis: Osteoarthritis caused by degenerative changes can cause pain after playing sports such as ball games because the cartilage and subchondral bone are stimulated by pressure. Rest, braking, physical therapy and hot compresses are needed. In severe cases, artificial joint replacement surgery can be performed. If the pain below the knee is not relieved for a long time after playing soccer, you need to consult a doctor in time, complete the relevant examinations, and receive appropriate treatment after clarifying the cause of the disease.