It is recommended to drink alcohol after three days of taking Roxithromycin. The current instructions for Roxithromycin do not specify how long you can drink alcohol after taking the drug orally, but try not to drink alcohol while taking the antibiotic to avoid some adverse reactions or causing aggravation of the primary disease. Oral medication has a certain metabolic process, it is recommended to drink after three days is safer. In addition, after taking oral erythromycin, it is also necessary to control the primary disease before going to drink alcohol, otherwise it may lead to prolonged or aggravation of the disease. Clinical oral antibiotic drugs are best not to drink, especially such as cefradine, metronidazole, ceftriaxone, etc., this kind of drug oral medication after drinking may cause disulfiram reaction.