In general, the severity of liver cancer growing on S6 segment cannot be assessed, S6 is a part of the liver, and the severity cannot be judged by this part alone, but needs to be combined with other clinical information. 1. Early stage liver cancer: in case of early stage liver cancer, generally speaking, the ideal treatment effect can be achieved through surgical treatment, so strictly speaking, it is not particularly serious, but it must be treated in time to avoid deterioration. 2. Middle and late stage: if the malignant tumor is large in size and has metastasis or differentiation in middle and late stage, it will be more serious, and this situation needs to be treated by immunotherapy, targeted therapy and other ways, and the treatment process is relatively more complicated. If there is S6 liver cancer, one should go to the hospital for examination immediately, actively cooperate with the doctor’s treatment, and carry out the corresponding treatment under the doctor’s guidance, and avoid indiscriminate use of medicines, so as not to miss the opportunity of illness.