Liver coarsening may refer to thickening of liver echoes, which is an abnormal manifestation of ultrasound. When there is thickening of liver echogenicity on ultrasound, it suggests that there are different degrees of fibrosis in the liver, and there are many clinical reasons that can cause fibrosis in the liver. Some diseases can be completely reversed, and fibrosis can gradually disappear, restoring normal liver shape and texture, such as drug hepatitis, fatty liver, alcoholic liver, etc. Some diseases can not be completely reversed, and fibrosis can gradually disappear, restoring normal liver shape and texture. While some diseases cannot be completely cured, the fibrosis of the liver can be well controlled to slow down the trend of cirrhosis, such as hepatitis C, hepatitis B, autoimmune liver disease, etc. Liver ultrasound is only a preliminary measure of liver fibrosis. If you want to know more about the extent of liver fibrosis, you can use liver transient elastography, which is performed by ultrasound, and liver fibrosis test, which is performed by drawing peripheral blood.