The correct way to take Isosorbide Nitrate is 5~10mg once, 2~3 times a day. Isosorbide nitrate can be used for long-term treatment of coronary heart disease, prevention of angina pectoris, chronic congestive heart failure, pulmonary hypertension and other diseases. For the prevention of angina pectoris, 5~10mg once, 2~3 times a day, due to differences in individual treatment, it can be adjusted according to the condition, the total amount of 10~30mg a day. isosorbide nitrate should be used under the guidance of a physician. Adverse reactions of isosorbide nitrate include vasodilatory headache, facial flushing, dizziness, hypotension, tachycardia, aggravation of angina, collapse, syncope and so on. Contraindications are acute circulatory failure, severe hypotension, acute myocardial infarction with low filling pressure, hypertrophic obstructive cardiomyopathy. If the condition requires the use of isosorbide nitrate, it should be used under the guidance of a doctor.