Patients with air leakage for 20 days after lung surgery can be treated with general therapy, medication and surgery under the guidance of a doctor. 1. General treatment: after lung resection surgery, air leakage is normal, patients need to rest in bed, follow the doctor’s instructions for care, pay attention to a light diet, eat more vitamin-rich foods to promote wound recovery, such as carrots, apples, etc., to strengthen the food nutrition. 2. Drug treatment: air leakage after lung surgery may also be caused by mild infection, patients can take antibiotics under the guidance of the doctor for treatment such as piperacillin, ceftriaxone, roxithromycin and other drugs. 3. Surgery: After lung surgery, if there is much air leakage, obvious compression of lung tissue, the air leakage is not relieved after closed chest drainage, and the air leakage time is long, after professional doctor’s evaluation, it is feasible to have another surgery. It is recommended that patients follow the doctor’s instructions for regular review after surgery, and go to the hospital for timely treatment of any discomfort.