At present, the commonly used methods for removing spots include laser spot removal, drug spot removal, etc. However, the optimal treatment programs for different spots are different, and there is no such thing as how to remove spots most reliably. 1. Laser spot removal: it is the more common and effective way to remove spots. Through laser irradiation, melanin particles are rapidly broken down and finally metabolized by macrophages in the body, so as to lighten or even remove the color spots. Usually, it requires 3 to 5 times of treatment and the price is relatively high. 2. Drugs to get rid of spots: Commonly used drugs to get rid of spots is to use depigmenting agents to lighten spots, and also inhibit tyrosinase synthesis of melanin, such as tretinoin cream, azelaic acid cream, hydroquinone cream and so on. Drug treatment needs to be used under the guidance of physicians, but most of the drug treatment can only lighten the pigmentation, generally as an auxiliary treatment. There are many kinds of ways to get rid of pigmentation, and those who are willing to have treatment are recommended to go to regular medical institutions and follow the advice of specialists to choose the most suitable treatment for themselves.