Among the diuretic drugs used clinically, the diuretic drug acting on medullary collaterals has the best effect, and the commonly used drug is furosemide injection. The usual dose is 10-400mg, the initial dose of 10mg can achieve rapid diuretic effect, but for some patients with poor renal function and less urine can gradually increase the dose, the maximum dose can be given 400g/24h, such as more than 400g/24h may cause the body’s toxic reaction. For patients with renal failure in urgent need of diuresis, you can also assist in renal vasodilator drugs, such as giving dopamine injection 60-80mg slowly drip, it is recommended to drip about 10-30ml per hour and adjust according to the rate of blood pressure rise. The use of dobutamine can make the kidney blood flow increase, the kidney filtration can be strengthened can be quickly diuretic, and at the same time auxiliary use of diuretic drugs acting on the medullary collaterals furosemide injection, can quickly achieve diuretic effect.