Scabies nodules and scabies differ in terms of etiology, treatment, and symptoms. 1. Etiology: Scabies nodules are localized inflammatory reactions caused by scabies infection, resulting in infiltration of inflammatory cells and proliferation of local skin tissues. Scabies is caused by the parasitization of the scabies mite on the human epidermis. 2. Treatment: The treatment of scabies nodules is mainly aimed at stopping itching, and can be treated by injecting glucocorticoids into the lesions, as well as with topical tacrolimus ointment, pimecrolimus cream and other drugs. If other treatments are not effective, the scabies nodules can also be surgically removed. In contrast, scabies is treated with the aim of killing the insects, along with anti-itch treatment. This disease is usually treated with medication, commonly used drugs are 10% benzoate lotion, 10% Clomid cream, 5% paracetamol, 40 sodium thiosulfate solution and so on. 3. Symptoms: Both scabies nodules and scabies produce itching symptoms. However, whereas scabies nodules form hard, red, pea-sized nodules, scabies only forms pimples, which are usually the size of a pinhead. Both scabies nodules and scabies can cause a lot of inconvenience, so it is important to seek medical attention as soon as possible and treat the condition aggressively as recommended by your healthcare provider.