Keratosis pilaris, medical generally refers to keratosis pilaris, the key to treatment is to soften the stratum corneum, reduce hypertrophy, and facilitate drug penetration. Accompanied by chaffing, it is appropriate to first use oil to relieve chaffing, without chaffing can be used to peel off the strong role of the drug, and then use antifungal drugs. 1. Keratinized tinea pedis refers to the foot fungus that manifests itself in diffuse thickening, desquamation, dryness, surface thickening and other symptoms, usually without itching, and most often occurs in the fall and winter. (1) accompanied by chafing, pain and bleeding patients, it is appropriate to first use oil relief such as erythromycin ointment and ketoconazole ointment mixed according to 1 to 1, mixed with castor oil and applied to the affected area. To be chapped after the improvement, and then apply ketoconazole ointment, terbinafine spray and so on. (2) no chaffing, stratum corneum hypertrophy of patients, it is appropriate to apply compound benzoic acid solution, to be thinned after the stratum corneum can be according to the general treatment of beriberi. If the effect is not good, can be applied on the basis of compound benzoic acid solution, wrapped in plastic wrap outside for half an hour, can effectively help soften the stratum corneum, and then with the external application of ketoconazole ointment, terbinafine spray. 2. Generally, the course of external antifungal drugs needs more than four weeks, if necessary, can also be combined with oral antifungal drugs such as itraconazole. The treatment should also pay attention to personal hygiene, try to choose breathable shoes and socks and change and wash them in time. It is recommended that patients with athlete’s foot go to the hospital, under the guidance of a dermatologist, the drugs should be used according to the doctor’s instructions, and should not abuse the drugs on their own, so as to avoid adverse reactions.