Lung cancer advanced stage with drowsiness is often caused by brain metastasis, if the patient’s vital signs are stable, radiotherapy or targeting can be considered to relieve the symptoms. Advanced lung cancer is often accompanied by brain metastasis, and the metastatic lesions compress the nerves, leading to drowsiness, vision loss, headache and other symptoms, and the prognosis is often unsatisfactory. If the patient’s other conditions are good and there is no contraindication to treatment, radiotherapy to the brain can be considered to shrink the lesion, which can alleviate the symptoms of drowsiness. Small molecule targeted drugs can pass the blood-brain barrier and reach the brain, which can be reasonably selected to improve the symptoms. Therefore, the prognosis of advanced lung cancer with drowsiness is often bad, and some patients can consider treatment to relieve the symptoms and improve the quality of life.