Herpes simplex is caused by infection with the human herpes simplex virus, and can be treated with topical medications and oral medications in the early stages of the disease. 1. Topical medications: Herpes simplex virus may cause recurrent erythema, clustered blisters and other skin lesions on the skin and mucous membranes, and can be treated with topical medications such as acyclovir cream and fusidic acid cream to inhibit local viral replication and reduce the risk of infection. 2. Oral medication: Herpes simplex is mainly caused by infection with herpes simplex virus, and can be treated with some antiviral medications, such as acyclovir, vasiclovir, and so on. If herpes simplex is diagnosed, it is recommended that the patient go to the hospital in time, choose the appropriate medication under the guidance of a professional doctor, and follow the doctor’s instructions to use the medication, so as not to cause adverse consequences. All of the above drugs should be used under the guidance of a doctor.