Middle lobe nodules in the lung refer to nodules in the middle lobe of the right lung. Combining the clinical manifestations of the patients and the morphology of the nodules, the following treatment methods are decided: i. If the patient has small nodules with smooth margins and the patient has no clinical symptoms, the nodules are considered benign and regular review is sufficient. If the nodule is large, with smooth edges and burrs, and the patient has fever, fatigue, wasting, coughing up blood, chest pain and other symptoms, malignant nodules are not excluded clinically, and relevant examinations are needed to improve the diagnosis, and if the nodule is diagnosed as malignant, surgery, radiotherapy, chemotherapy, target cell drug therapy, etc. should be considered. Third, if the nodules are caused by pathogenic bacteria, it is necessary to further improve the relevant examination to clarify the pathogenic bacteria and make targeted treatment.