There is no such thing as which antihypertensive drug is the best for hypertension. Different types of antihypertensive drugs are suitable for different individuals and need to be selected and taken under the guidance of a doctor. Hypertension is usually treated with antihypertensive drugs, and there are five major classes of antihypertensive drugs in common use, divided into diuretics, calcium antagonists, beta-blockers, angiotensin-converting enzyme inhibitors, and angiotensin II receptor antagonists. Diuretics (hydrochlorothiazide, furosemide, etc.) are suitable for simple systolic senile hypertension, and the antihypertensive effect of diuretics is better in these patients. Angiotensin-converting enzyme inhibitors (enalapril, perindopril, ramipril) and angiotensin II receptor antagonists (valsartan, candesartan) are suitable for patients with hypertension combined with diabetes mellitus and nephropathy, and these two types of antihypertensive drugs, in addition to the effect of lowering blood pressure, have a certain degree of protection of renal function. Beta-blockers (metoprolol, propranolol) are suitable for hypertensive patients with faster heart rate, and are more effective in young hypertensive patients with more sympathetic nerve excitation. Calcium antagonists (nifedipine, amlodipine) have the effect of dilating the coronary arteries, so patients with hypertension combined with coronary atherosclerosis take this type of antihypertensive drugs are more effective, not only can lower blood pressure can also alleviate the symptoms of coronary heart disease chest pain. The choice of antihypertensive drugs need to follow the doctor’s instructions, the doctor will guide the appropriate medication according to the patient’s specific situation, not blindly and indiscriminately.