Patients with ALT (alanine aminotransferase) rebound after discontinuation of bupropion can continue to take the medication and still be effective if there is no jaundice or worsening of the condition. Bifenazate is often used in chronic hepatitis or chemical toxicity, drugs and other causes of ALT elevation, after stopping the drug, some patients will appear ALT rebound, continue to take the drug is still effective. However, it should be noted that if jaundice or deterioration of the original condition occurs during the course of taking the drug, the drug should be stopped promptly. In addition, biphenyl dibenzoate can not be used in cirrhosis-induced ALT elevation, pregnant women and lactating women are also prohibited from using this drug, elderly patients should be cautious in the application of this drug. Common adverse reactions include dry mouth, mild nausea, and occasionally rash. It is recommended that patients avoid self-medication, and should consult a doctor in time for liver function abnormalities, clarify liver function tests (liver biochemistry, liver ultrasound, chest CT, etc.), and give regular treatment after clarifying the cause of the disease, in order to reap the best prognosis.