Pain in the cheeks when eating may be temporomandibular joint disorder, acute wisdom tooth pericoronitis, oral mucosal diseases, etc. 1. Temporomandibular joint disorder: eating and opening the mouth and cheek pain may be temporomandibular joint disorder, there may also be limited opening of the mouth, joint popping and other symptoms. 2. Wisdom tooth pericoronitis: pain in the cheeks when eating may be due to inflammatory diseases such as wisdom tooth pericoronitis, which may involve the chewing muscles in the acute stage. 3. Oral mucosal diseases: oral mucosal diseases on the buccal mucosa, such as oral leukoplakia, lichen planus and other oral vesiculoblastic diseases, the patient will have pain in the cheeks when eating. Eating open mouth cheek pain may also have other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.