Colon cancer is a relatively common malignant tumor in clinic, and colon cancer patients can be treated with moxibustion. Moxibustion is a kind of therapeutic means in Chinese medicine, which can stimulate the activity of essence and qi in the body through stimulation of specific parts, so that metabolic disorders can be adjusted to achieve the purpose of curing and preventing diseases. Through moxibustion treatment, it can reduce the side effects of radiotherapy and can play a role in sensitizing radiotherapy. Moxibustion can improve the body’s immunity is undoubtedly, in the clinical research of several scholars, moxibustion for the treatment of colon malignant tumors, can significantly improve the patient’s weakness, especially fatigue, heat, body fatigue, lumbar and knee soreness and so on with remarkable results. Moxibustion can improve the quality of life of tumor patients, and has an important role in inhibiting the growth of colon cancer cells.