Amlodipine can generally be taken together with vitamin D3. Clinically amlodipine belongs to the calcium channel blocker drug, after taking it can reduce the extracellular calcium ions into the vascular smooth muscle cells, reduce the contractile response of resistance vessels, mainly used for hypertension, angina pectoris and other diseases treatment. Amlodipine may cause dizziness, headache, nausea, vomiting, edema and other discomforts after taking it. It is forbidden for those who are allergic to the components of liver drugs, and in the process of taking the drug, you need to pay attention to low blood pressure, aggravation of angina pectoris, impaired liver function, etc., while pregnant women and lactating women need to use the drug under the guidance of a doctor. Vitamin D3 belongs to the vitamin class of drugs, after taking can promote the absorption of calcium and renal tubular reabsorption of phosphorus, improve the concentration of blood calcium, blood phosphorus, mainly used for the prevention and treatment of vitamin D deficiency. Vitamin D3 may cause constipation, diarrhea, nausea, vomiting and other discomforts. It is contraindicated for people with hypercalcemia and vitamin D increase. In the process of taking the drug need to regularly review the blood calcium and other related indicators, while pregnant women, lactating women need to use the drug under the guidance of a doctor. There is no drug that can not be taken together with amlodipine. There are no contraindications to taking vitamin D3 with calcium channel blockers in the drug interactions of vitamin D3. There are no contraindications to their use in combination. Usually, amlodipine and vitamin D3 can be taken together when the respective indications for amlodipine and vitamin D3 are present and contraindications have been ruled out. If you need to take amlodipine and vitamin D3 together because of your condition, it is recommended that you consult a doctor in a timely manner to determine the dose of the medication after a comprehensive assessment of your condition, and follow the doctor’s instructions to standardize the use of the above medications.