Looking at the current state of affairs, many accidents are happening all around us. When a cranial defect occurs, many patients are very afraid, both of the dangers of not repairing it and of the risks associated with repair surgery. In fact, cranial repair is just a routine procedure in neurosurgery to achieve coverage of the defect with little risk of failure. The most important thing for the patient to achieve the purpose of the surgery is the choice of the repair material. What is the material for cranial repair? I believe that many hospitals preferred titanium mesh, as the most widely used cranial bone repair material, although the price is easy to make the public accept, but it is not the best repair material, some patients after using titanium mesh appeared in different degrees of rejection, and even the phenomenon of titanium mesh leakage. What is the best cranial bone repair material? The emergence of a new material, polyether ether ketone material, commonly known as peek material, has brought good news to many patients with cranial defects. Speaking of its advantages compared to titanium mesh, in addition to the price is slightly more expensive than titanium mesh, the rest of the convenience of all the more outstanding, peek material insulation, the patient’s repair will not be because of the change of the weather environment has any feeling; it has excellent mechanical properties, strong resistance to impact, can effectively protect the human brain tissue; from the point of view of the appearance of the beauty of the peek material is based on the patient’s brain CT data, and 3D printing technology is used to produce a skull that perfectly matches the bone window; as a non-metallic material, it is stable, can be repeatedly sterilized by high temperature and high pressure, and there is no risk of surgical infection, thus reducing the occurrence of complications. Therefore, cranial repair with peek material is a better choice for many people.