H. pylori positive patients need to be treated with quadruple therapy with omeprazole, bismuth, and 2 antibiotic drugs under the supervision of a physician. H. pylori positive patients need to take three types of drugs; the first type of drugs is proton pump inhibitors such as omeprazole, rabeprazole, etc.; the second type of drugs is bismuth, commonly used bismuth silver citrate, bismuth pectin, etc.; the third type of drugs is antibiotics, commonly used antibiotic drugs are clarithromycin, metronidazole, amoxicillin, tetracycline, etc.. Combined treatment of the above four drugs for two weeks can generally achieve the role of eradicating H. pylori; four weeks after stopping the drug need to be rechecked for H. pylori; pay attention to ask the patient whether there is a history of drug allergies during the medication. It is recommended that the above drugs be taken under the guidance of a professional doctor, and should not be taken privately to avoid adverse effects.