The probability of contracting an infectious disease from platelet donation at a regular blood donation center is very low. The instruments used for platelet collection are usually disposable, undergo strict sterilization procedures and are used within the validity period. Every donor will undergo a simple health check and blood test before donation, which ensures the health and safety of both the donor and the recipient of the platelets. So the likelihood of cross-infection is very low at a regular blood donation center. Platelet donation should also be done according to one’s own situation and it is best if one has donated whole blood before and all the indicators of the body meet the criteria for platelet donation. Don’t do strenuous activities after donating platelets, and go to the hospital as soon as possible if you feel unwell.