Primary hand sweating is often caused by an abnormally high excitation of the sympathetic nerves that innervate the sweat glands in the hands, resulting in excessive sweating of the hands regardless of external temperature. It usually begins in childhood or adolescence, and some patients have a family history of hand sweating. Although hand sweating is not a health problem, the uncontrollable sweating often causes a lot of inconvenience and embarrassment in school, life, work and social life, and even affects physical and mental health. According to Lai hand sweat classification: mild: palm sweating increased, moist, but can not wet a handkerchief; moderate: palm sweating significantly increased, can wet a handkerchief; severe: palm sweating a lot, drip bead-like. The treatment for hand sweating is currently mainly medical treatment and surgical treatment. However, the effect and duration, complications, and cost of each method of treatment are different. The actual botulinum toxin is a neurotoxin produced by the anaerobic Clostridium botulinum, which can be used to remove wrinkles and beauty, and can also inhibit the release of acetylcholine at the sympathetic nerve junction that governs the sweat glands, thus improving the sweaty hands. However, its treatment requires subcutaneous injection, which is very painful and requires local anesthesia, and is only effective for 4 to 6 months. And expensive, in many cosmetic wrinkle patients in the follow-up application of a lot of side effects, so it is not easy to promote the application. 2.Oral sedatives, anticholinergic drugs and other western medicine treatment, but easy to cause dry mouth, tachycardia and other side effects, and the effect is not obvious. 3, external astringent, antiperspirant, etc., by blocking the sweat gland secretion duct and promote the atrophy of sweat glands to play a role, but must be repeated every 24 to 48h, minor hand sweating also need 3 weeks after the effect, and easy to relapse after stopping the drug. Surgical treatments include: Thoracoscopic thoracic sympathectomy is the most effective and long-lasting method for treating hand sweating. Because of the small trauma, good exposure, accurate positioning, safe and reliable, fast recovery, satisfactory and long-lasting efficacy, and the ability to complete bilateral surgery at the same time, patients are happy to accept the television thoracoscopic surgery. At present, the use of needle thoracoscopic thoracic sympathetic nerve severing treatment for hand sweating is more minimally invasive, does not require sutures, does not leave any scars, and has achieved very satisfactory results. One side of the operation takes 8-15 min, 12 min on average, and the whole hospitalization cost is about 7000-9000 RMB. No chest drainage tube is placed after surgery, and the patient can be discharged on the second day after surgery. The effect of the operation is immediate, and the palm of the hand is warm and dry without sweating after the operation, and the haze that has been over the patient’s heart for many years is completely dispelled, and he can live a normal life from now on.