The patient’s mouth suddenly crooked may be acute cerebrovascular disease or peripheral facial neuritis, need to address the causes of symptomatic treatment: 1, if the facial neuritis caused by the acute period, there is no contraindication to the use of hormones, you can give the patient through the hormone treatment, and at the same time to give the patient oral methylcobalamin, adenosine cobaltamine, vitamin B12, these drugs nutritional nerve treatment. After one week in the acute stage, acupuncture can be used to help patients recover from facial paralysis; 2. If it is caused by acute cerebrovascular disease, such as cerebral infarction, the patient should be given treatment to activate blood circulation and improve blood circulation in the brain in the early stage. If there is no contraindication to thrombolysis, the drug treatment of thrombolysis needs to be given, and intravenous thrombolysis can be carried out through static rtPA or urokinase. If you miss the time window for thrombolysis, you can choose to lower the fiber, anticoagulation, antiplatelet treatment to promote the recovery of neurological function and improve the patient’s symptoms of sudden crooked mouth.