The main causes of pressure pain in the first joint of the index finger include aseptic inflammation and carpal tunnel syndrome. 1. Aseptic inflammation: mainly including tenosynovitis, gout, bursitis, rheumatoid arthritis and other diseases, due to prolonged wear and tear, degenerative bone and joint diseases, urate deposition and other reasons, resulting in increased exudation of joint soft tissues, edema, tendon sheaths, tendon sheaths, and even joint deformity, the formation of aseptic inflammation, the emergence of pain symptoms. 2. Carpal tunnel syndrome: also known as “mouse hand”, belongs to a class of diseases of peripheral nerve injury, the carpal tunnel contains tendons, ligaments, median nerve and other soft tissues, when a variety of factors lead to the median nerve by the cardinal pressure, it will produce the anterior part of the carpal tunnel and the hand and other innervated areas of the performance of numbness, pain, weakness, and in severe cases, the patient can also Muscle atrophy may also occur. The first section of the index finger pressure pain may also have other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.