We often encounter patients with epilepsy in outpatient clinics who have had an MRI and have cavernous hemangioma as a result. We would like to popularize the symptoms associated with cavernous hemangioma and epilepsy here. Epilepsy is the most common symptom of cavernous hemangioma in the brain (38%-100%). Drug-refractory epilepsy occurs in about 1/3 of these patients. The occurrence of epilepsy is associated with recurrent hemorrhage from the hemangioma, iron-containing heme deposits, and gliosis. Surgical resection of the tumor is the treatment of choice for intracranial cavernous hemangioma, with the goal of removing the largest possible lesion with the least possible damage. Intracerebral cavernous hemangioma is relatively easy to remove because of the lack of obvious blood supply arteries and the clear boundary between the lesion and the surrounding brain tissue, except for the lesion located in the brainstem. Mao Renling’s neurosurgery team has learned that using neuronavigation-assisted microsurgery techniques to avoid functional areas as much as possible can reduce surgical damage and significantly reduce the incidence of postoperative complications. The lesion, iron-containing heme deposits, and glial hyperplasia zone should be removed surgically. We have used the above-mentioned methods to achieve the disappearance of postoperative epilepsy in the above-mentioned patients, and the excised specimens were examined histologically and confirmed to be gliosis with varying degrees of iron-containing hemoglobin deposits.