Itchy bumps on the palms of the hands are a symptomatic manifestation of many diseases, such as eczema, hives and other diseases. It is recommended that patients clarify the cause of the disease and be treated with medication. 1. Eczema: due to allergies, chemical stimulation, etc., easy to cause localized eczema. Localized erythema and papules appear, and in severe cases, blisters merge into patches. It is recommended to stay away from allergens as soon as possible, and to take antihistamines such as loratadine and antibiotics such as amoxicillin as prescribed by the doctor. Sweat herpes, is a special type of eczema, the patient usually manifests as small blisters deep in the epidermis, not red around, in the gradual drying of the flakes, may be accompanied by itching. Patients are advised to use glucocorticosteroid drugs such as dexamethasone and antihistamines such as loratadine as prescribed by the doctor. 2. Urticaria: caused by internal and external allergies, infections and other factors, manifested as red spots, wind masses with itching, it is recommended that patients use external glycerine lotion, oral loratadine and other antihistamines. Itchy pimples on the palms of the hands recommend timely access to the hospital, under the guidance of the doctor reasonable use of medication, do not self-medication.