Whether fever affects transaminases in infants and young children needs to be judged according to the cause of the fever, such as fever caused by liver disease, which may cause transaminases to rise. Transaminase is one of the items of liver function tests. When liver cells are inflamed, poisoned, or necrotic, it can cause damage to liver cells, and the transaminase will be released into the bloodstream, causing the serum transaminase to be elevated, which is mainly seen in certain patients with hepatitis. Fever in infants and young children, need to improve the relevant examination to clarify the cause of the disease. If the fever is caused by liver disease, such as viral hepatitis fever, check liver function, can be seen in alanine aminotransferase, glutamic oxal transaminase obviously elevated, and accompanied by nausea, vomiting, fatigue, skin sclera yellow stain and other symptoms. If the fever is caused by other diseases such as upper respiratory tract infection, it usually does not affect the transaminases. However, taking certain antibiotics or fever-reducing drugs when having a fever may cause damage to the liver and cause transaminases to rise. If transaminases are found to be abnormal in infants and young children with fever, it is important to seek medical attention to determine the cause of the illness and to treat the primary illness.