Trazodone and mirtazapine are both antidepressants, but the two drugs are of different types and have different therapeutic effects, so they cannot be replaced at will. Mirtazapine has been found in clinical trials to have a sedative effect, a good effect on sleep improvement, can promote sleep, prolong sleep time, long-term use of sleeping pills are addictive and mirtazapine is more secure. Trazodone also has a sleep-aiding effect, small doses are used to treat insomnia, and large doses can improve the symptoms of anxiety and depression in patients. So if you suffer from depression or sleep disorders, doctors will choose different drugs for treatment according to the patient’s situation, due to individual differences in the situation, case by case. In order to avoid delays, it is recommended to go to the hospital in time to clarify the condition and give standardized treatment. Drugs need to be used under the guidance of a physician, no matter what the drug do not replace and increase or decrease the amount.