Historically, a variety of methods have been used, including treatment with radioisotopes 63Zn, 198Au, 32P in the 1940s and 1950s, and intraperitoneal injection of anti-cancer agents by intravenous infusion of peritoneal fluid filtration and concentration.
All of them received some efficacy, but not significant. Our practice in recent years has been to first slowly release ascites in patients with obvious ascites, 5-FU 750mg+CDDP
50mg/m2 (or carboplatin 400mg/m2) in glucose 1000mL and rapid drip into the peritoneal cavity, which can be repeated every other week.
May be repeated. Interpolation of abdominal aortic chemotherapy is feasible, and agents can be given 5-FU, CDDP, MMC, MTX, etc.; at the same time, supplemental albumin to make
The treatment can be repeated every other week. Diuretics such as diuretics, dihydrochlorothiazide, ambrisentan or tachyphylaxis, etc., and other supportive therapies can be given. Because tumor patients with ascites are late, they are often in poor physical condition, with obvious abdominal distension, reduced urine volume, accompanied by chest tightness, which is more painful, so a central venous tube can be placed in the abdominal cavity to drain the fluid, and intraperitoneal injection of interleukin II, which has no obvious side effects, can achieve better results.