The increase of lymph nodes may be caused by infection, allergy, autoimmune disease, malignant tumor disease and so on. 1. Infection: when the patient’s body has bacterial, viral infection and tuberculosis infection, some of the lymph nodes may be enlarged, palpation can touch some parts of the lymph nodes increase in size, increase in the situation, the patient needs to consult a doctor in time for examination and targeted treatment. 2. Allergy: when the patient is exposed to allergens such as paint and pollen, it may cause allergy, which may lead to lymph node enlargement, the patient needs to get rid of the allergens in time, and seek medical treatment in time. 3. Autoimmune disease: autoimmune disease refers to the body’s immune response to its own antigen and caused by the disease. If you suffer from lupus erythematosus, immune thyroiditis, rheumatoid arthritis and other diseases, it may cause an increase in lymph nodes. 4. Malignant tumors: lymphoma, lymphoblastic leukemia, lymphatic metastasis of malignant tumors can lead to enlargement of invaded lymph nodes, which can be easily detected by palpation or ultrasonography, and increase in lymph nodes in these areas. Therefore, if you find localized lymph node increase in your body, you should have further examination in time, and follow the doctor’s prescription for treatment after clear diagnosis.