Toxoplasma gondii infection in late pregnancy requires further examination to clarify whether the fetus is infected intrauterine, and at the same time can be treated with medication accordingly. Toxoplasma gondii infection in late pregnancy has a high probability of intrauterine fetal infection, and the rate of intrauterine infection is 71% for those who are infected after 36 weeks. Most of the intrauterine infected children do not have obvious characteristics of toxoplasmosis when they are born, and then they may develop neurological symptoms such as hepatosplenomegaly, jaundice, anemia, intracranial calcification, hydrocephalus, microcephaly, etc. They can also develop into choroidal retinitis and learning disabilities. When a pregnant woman is found to be infected with Toxoplasma gondii in late pregnancy, the first step is to evaluate the condition of the fetus in the uterus and clarify whether there is any intrauterine infection occurring by means of pathogenetic examination, serologic examination and imaging examination. Toxoplasma infections in late pregnancy are mainly treated with medication, which can be acetylspiramycin under doctor’s supervision. Pregnant women infected after 18 weeks of gestation or those suspected of being infected can be treated with a combination of acetamiprid, sulfadiazine and formyltetrahydrofolate. The combination of drugs is more effective than a single drug at killing Toxoplasma gondii through the placenta and reducing the severity of complications in children with intrauterine infections. Toxoplasma gondii infection in late pregnancy, you need to consult a doctor in a timely manner, under the guidance of the doctor’s treatment, the use of medication should be strictly comply with the doctor’s instructions to implement, can not be arbitrarily used on their own.