Blackheads on the nose with large pores, usually due to sebum, bacteria in the pores of the collection and become, need to choose drugs, physical, general treatment methods to improve. 1. Drugs: blackheads on the nose with large pores is considered to be caused by excessive sebum secretion or increased secretion of androgens in the body. Patients can apply adapalene gel, tazarotene cream and other drugs under the guidance of the doctor, which can play a role in removing blackheads, but also improve the pore size. 2. Physical: If the patient’s condition is more serious and cannot be relieved after medication, he can also choose fruit acid peeling treatment, which can play the role of exfoliation, oil control, and also improve the clogging of hair follicles to remove blackheads on the nose. 3. General treatment: patients need to keep the nose area clean and clean, need to use warm water when washing the face, do not use irritating cosmetics, do a good job of skin moisturizing sunscreen. Patients with blackheads on the nose with large pores need to follow the doctor’s instructions to choose the treatment, but also can not privately use their hands to squeeze the blackheads, in order to avoid triggering an infection.