Because the knee is the main weight-bearing joint of the body, osteoarthritis of the knee can lead to serious functional impairment. Most of the previous treatments can only provide short-term relief and cannot stop the progression of the disease, but also aggravate the degeneration of joint cartilage. Sodium vitrate is a safe, ideal and effective drug for the treatment of osteoarthritis, but this year there is controversy at home and abroad as to the stage of the disease in which to inject sodium vitrate. Walking up and down the stairs without pain? Wrong! In fact, this is not true. Under the action of various pathogenic causes, the synovial membrane composition of the joint cavity changes and the content of sodium vitrate decreases or the joint function decreases, resulting in the corrosion and destruction of joint cartilage, which slowly produces pain and leads to impaired movement over time. Many years of clinical cases have proved that if elderly people with early to mid-stage knee osteoarthritis go to the hospital for sodium vitrate injection in time, it can well reduce the friction between joint bones and promote their own sodium vitrate and synthesis of proteoglycan and collagen, improve the metabolism of synovial membrane and cartilage, delay the degeneration of knee joints, and minimize the lesions brought about by knee osteoarthritis. In other words, the earlier the sodium vitrate is injected, the better, so do not wait until you need to use crutches to walk before you rush to inject it. However, exogenous sodium vitrate can increase the content of sodium vitrate in the synovial membrane, re-form the natural barrier and prevent further destruction of the cartilage matrix; improve the biological function of the synovial membrane in the pathological state, increase joint lubrication and reduce joint friction. Physical effects, to relieve the pain of the knee joint or have a certain role. The injection technique is important Generally speaking, the treatment of sodium vitrate is once a week, and a course of 3~5 times can complete the replenishment of sodium vitrate. However, there are many elderly people who say that they feel a recurrence of pain in the knee joint several years after the injection, which is actually due to the imperfect injection method of puncturing into the knee joint cavity. Furthermore, knee osteoarthritis is a long lifelong disease that requires patients to be prepared for long-term prevention and not to have the idea of “one cure for life”.