There are many causes of abdominal vague pain and blood in stool, which can be roughly divided into two kinds of non-tumor diseases and tumor diseases. Patients need to actively seek medical advice to clarify the cause and treat the cause. I. Non-neoplastic diseases 1, inflammatory diseases: such as ulcerative colitis, Crohn’s disease, etc., manifesting as abdominal pain, mucopurulent stools, perianal fistula formation and other symptoms. Can be treated with salazosulfapyridine, mesalazine, with intestinal probiotics; 2, immune diseases: such as allergic purpura, can be manifested as abdominal pain, blood in the stool. If abdominal pain, vomiting and blood in stool are serious, glucocorticoids can be used. 3. Infectious diseases: such as acute bacterial dysentery, which is characterized by rapid onset, high fever, nausea and vomiting, abdominal pain, shortness of breath, pus and blood in stool, etc. Severe cases may also have incontinence. In addition to oral rehydration, intravenous rehydration is required under the guidance of a doctor, and quinolone antibiotics are also used; 4. Systemic diseases: such as uremia, some patients will have mucosal erosion and ulcers in the gastrointestinal tract, and abdominal pain and blood in the stool can also occur, which requires suppression of gastric acid and application of gastric mucosal protective agents. Second, tumor disease colorectal cancer: early stage is often asymptomatic, and symptoms such as blood in stool and abdominal pain appear after the disease progresses, which requires histopathological biopsy for clarification and comprehensive consideration of treatment means according to clinical staging. Regardless of the causes of abdominal pain and blood in stool, we need to pay attention to diet in daily life, eat easily digestible and nutritious food appropriately, and avoid spicy and stimulating food such as chili and mustard to improve gastrointestinal function and prevent blood in stool.