The causes of nocturnal sleep discomfort in the heart may be multifaceted, as follows: 1. Patients with coronary artery disease and poorly controlled myocardial ischemia may experience episodes of myocardial ischemia at night resulting in chest discomfort, and it is recommended that coronary imaging be given to clarify the degree and location of coronary artery stenosis and, if necessary, to give treatment for blood flow reconstruction. 2. For patients with variant angina pectoris, in the state of sleep at night The spasm of coronary artery often occurs due to the disturbance of vegetative nerves, which leads to myocardial ischemia, and may also lead to the uncomfortable feeling of heart in the sleep state. 3. Patients with cardiac insufficiency may also suffer from the uncomfortable state at night due to the increase of venous blood return to the heart by sleeping in the flat position at night, which leads to the increase of heart load, and patients may experience sudden gasping for breath during sleep at night and need to sit up to breathe. It is recommended to give standardized anti-heart failure treatment and systemic treatment for the cause.